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Abnormal gametogenesis induced by p53 deficiency promotes tumor progression and drug resistance
The century-old embryonal/gametogenesis hypothesis of tumors could link diverse tumors’ malignant features together likely representing the real “stemness” of tumors. However, the genetic evidence to validate abnormal gametogenesis in tumors remains lacking. Here we show that p53 deficiency elicits...
Autores principales: | Liu, Chunfang, Cai, Zhen, Jin, Guoxiang, Peng, Danni, Pan, Bo-Syong, Zhang, Xian, Han, Fei, Xu, Xiaohong, Lin, Hui-Kuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167385/ https://www.ncbi.nlm.nih.gov/pubmed/30302273 http://dx.doi.org/10.1038/s41421-018-0054-x |
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