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Magnesium Isoglycyrrhizinate Ameliorates Fibrosis and Disrupts TGF-β-Mediated SMAD Pathway in Activated Hepatic Stellate Cell Line LX2

Liver fibrosis is a histological change often attributed to the activation of hepatic stellate cells (HSCs) and the excessive formation of scar tissues in the liver. Advanced stages of the disease frequently lead to cirrhosis. Magnesium isoglycyrrhizinate (MgIG) has been accepted as a hepatoprotecti...

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Detalles Bibliográficos
Autores principales: Tee, Jie Kai, Peng, Fei, Tan, Yeong Lan, Yu, Bo, Ho, Han Kiat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167412/
https://www.ncbi.nlm.nih.gov/pubmed/30319402
http://dx.doi.org/10.3389/fphar.2018.01018