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Age-Dependent Anti-migraine Effects of Valproic Acid and Topiramate in Rats

Background: Valproic acid (VPA) and topiramate (TPM), initially developed as antiepileptics, are approved for migraine prophylaxis in adults but not children. The differences in their antimigraine mechanism(s) by age remain unclear. Methods: A migraine model induced by intra-cisternal (i.c.) capsaic...

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Detalles Bibliográficos
Autores principales:	Huang, Pokai, Kuo, Ping-Hung, Lee, Ming Tatt, Chiou, Lih-Chu, Fan, Pi-Chuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167431/ https://www.ncbi.nlm.nih.gov/pubmed/30319425 http://dx.doi.org/10.3389/fphar.2018.01095

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