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Autophagy Is Indispensable for the Self-Renewal and Quiescence of Ovarian Cancer Spheroid Cells with Stem Cell-Like Properties

Epithelial ovarian cancer has the highest mortality rate of all gynecologic cancers. Cancer stem cells are considered to be the initiating cells of tumors. It is known that spheroid culture promotes ovarian cancer cells to acquire stem cell characteristics and to become stem cell-like. But the mecha...

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Detalles Bibliográficos
Autores principales: Wang, Qian, Bu, Shixia, Xin, Dedong, Li, Boning, Wang, Lan, Lai, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167563/
https://www.ncbi.nlm.nih.gov/pubmed/30319732
http://dx.doi.org/10.1155/2018/7010472