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N-cadherin in cancer metastasis, its emerging role in haematological malignancies and potential as a therapeutic target in cancer
In many types of solid tumours, the aberrant expression of the cell adhesion molecule N-cadherin is a hallmark of epithelial-to-mesenchymal transition, resulting in the acquisition of an aggressive tumour phenotype. This transition endows tumour cells with the capacity to escape from the confines of...
Autores principales: | Mrozik, Krzysztof Marek, Blaschuk, Orest William, Cheong, Chee Man, Zannettino, Andrew Christopher William, Vandyke, Kate |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167798/ https://www.ncbi.nlm.nih.gov/pubmed/30285678 http://dx.doi.org/10.1186/s12885-018-4845-0 |
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