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Foxf2 plays a dual role during transforming growth factor beta-induced epithelial to mesenchymal transition by promoting apoptosis yet enabling cell junction dissolution and migration

BACKGROUND: The most life-threatening step during malignant tumor progression is reached when cancer cells leave the primary tumor mass and seed metastasis in distant organs. To infiltrate the surrounding tissue and disseminate throughout the body, single motile tumor cells leave the tumor mass by b...

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Detalles Bibliográficos
Autores principales: Meyer-Schaller, Nathalie, Heck, Chantal, Tiede, Stefanie, Yilmaz, Mahmut, Christofori, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167826/
https://www.ncbi.nlm.nih.gov/pubmed/30285803
http://dx.doi.org/10.1186/s13058-018-1043-6