Cargando…

Foxf2 plays a dual role during transforming growth factor beta-induced epithelial to mesenchymal transition by promoting apoptosis yet enabling cell junction dissolution and migration

BACKGROUND: The most life-threatening step during malignant tumor progression is reached when cancer cells leave the primary tumor mass and seed metastasis in distant organs. To infiltrate the surrounding tissue and disseminate throughout the body, single motile tumor cells leave the tumor mass by b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Meyer-Schaller, Nathalie, Heck, Chantal, Tiede, Stefanie, Yilmaz, Mahmut, Christofori, Gerhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167826/ https://www.ncbi.nlm.nih.gov/pubmed/30285803 http://dx.doi.org/10.1186/s13058-018-1043-6

Ejemplares similares

Breast cancer as an example of tumour heterogeneity and tumour cell plasticity during malignant progression
por: Lüönd, Fabiana, et al.
Publicado: (2021)

miR-1199-5p and Zeb1 function in a double-negative feedback loop potentially coordinating EMT and tumour metastasis
por: Diepenbruck, Maren, et al.
Publicado: (2017)

Py2T Murine Breast Cancer Cells, a Versatile Model of TGFβ-Induced EMT In Vitro and In Vivo
por: Waldmeier, Lorenz, et al.
Publicado: (2012)

Inferring signalling dynamics by integrating interventional with observational data
por: Cardner, Mathias, et al.
Publicado: (2019)

Molecular mechanism of double Holliday junction dissolution
por: Swuec, Paolo, et al.
Publicado: (2014)

The FAK inhibitor BI 853520 exerts anti-tumor effects in breast cancer
por: Tiede, Stefanie, et al.
Publicado: (2018)

Antisense lncRNA FOXF1-AS1 Promotes Migration and Invasion of Osteosarcoma Cells Through the FOXF1/MMP-2/-9 Pathway
por: Kun-Peng, Zhu, et al.
Publicado: (2017)

Machine-Vision-Enabled Salt Dissolution Analysis
por: Štukelj, Jernej, et al.
Publicado: (2020)

Top3α Is Required during the Convergent Migration Step of Double Holliday Junction Dissolution
por: Chen, Stefanie Hartman, et al.
Publicado: (2014)

FOXF2 oppositely regulates stemness in luminal and basal-like breast cancer cells through the Wnt/beta-catenin pathway
por: Zhang, Xiao, et al.
Publicado: (2022)

FoxF1 and FoxF2 transcription factors synergistically promote Rhabdomyosarcoma carcinogenesis by repressing transcription of p21(Cip1) CDK inhibitor
por: Milewski, David, et al.
Publicado: (2016)

FOXF1 Mediates Endothelial Progenitor Functions and Regulates Vascular Sprouting
por: Sturtzel, Caterina, et al.
Publicado: (2018)

FOXF2 reprograms breast cancer cells into bone metastasis seeds
por: Wang, Shuo, et al.
Publicado: (2019)

FOXF2 acts as a crucial molecule in tumours and embryonic development
por: He, Weihan, et al.
Publicado: (2020)

The regulatory roles and mechanisms of the transcription factor FOXF2 in human diseases
por: Wu, Qiong, et al.
Publicado: (2021)

FOXF2 Regulates PRUNE2 Transcription in the Pathogenesis of Colorectal Cancer
por: Li, Ting, et al.
Publicado: (2022)

Klf4 Is a Transcriptional Regulator of Genes Critical for EMT, Including Jnk1 (Mapk8)
por: Tiwari, Neha, et al.
Publicado: (2013)

Correction: Klf4 Is a Transcriptional Regulator of Genes Critical for EMT, Including Jnk1 (Mapk8)
por: Tiwari, Neha, et al.
Publicado: (2013)

Lethal lung hypoplasia and vascular defects in mice with conditional Foxf1 overexpression
por: Dharmadhikari, Avinash V., et al.
Publicado: (2016)

Association of FOXF2 gene polymorphisms with ischemic stroke in Chinese Han population
por: Shi, Chang-He, et al.
Publicado: (2017)

FOXF1 transcription factor promotes lung regeneration after partial pneumonectomy
por: Bolte, Craig, et al.
Publicado: (2017)

FOXF1 is required for the oncogenic properties of PAX3-FOXO1 in rhabdomyosarcoma.
por: Milewski, David, et al.
Publicado: (2021)

Perturbation of semaphorin and VEGF signaling in ACDMPV lungs due to FOXF1 deficiency
por: Karolak, Justyna A., et al.
Publicado: (2021)

Prenatal Detection of a FOXF1 Deletion in a Fetus with ACDMPV and Hydronephrosis
por: Bzdęga, Katarzyna, et al.
Publicado: (2023)

Reduced FOXF1 links unrepaired DNA damage to pulmonary arterial hypertension
por: Isobe, Sarasa, et al.
Publicado: (2023)

Saltatory formation, sliding and dissolution of ER–PM junctions in migrating cancer cells
por: Dingsdale, Hayley, et al.
Publicado: (2013)

Gap junction protein beta 4 plays an important role in cardiac function in humans, rodents, and zebrafish
por: Okamoto, Ryuji, et al.
Publicado: (2020)

The effect of absorbed hydrogen on the dissolution of steel
por: Thomas, Sebastian, et al.
Publicado: (2016)

Regulation of Lens Gap Junctions by Transforming Growth Factor Beta
por: Boswell, Bruce A., et al.
Publicado: (2010)

A Shh-Foxf-Fgf18-Shh Molecular Circuit Regulating Palate Development
por: Xu, Jingyue, et al.
Publicado: (2016)

Stroke-associated intergenic variants modulate a human FOXF2 transcriptional enhancer
por: Ryu, Jae-Ryeon, et al.
Publicado: (2022)

Stromal FOXF2 suppresses prostate cancer progression and metastasis by enhancing antitumor immunity
por: Jia, Deyong, et al.
Publicado: (2022)

Rare to “Ubiquitinous”: Alveolar Capillary Dysplasia, FOXF1, and a Sly Approach to Angiogenesis
por: Cornfield, David N., et al.
Publicado: (2023)

Generation of double Holliday junction DNAs and their dissolution/resolution within a chromatin context
por: Ho, Han N., et al.
Publicado: (2022)

Hierarchical Nanotexturing Enables Acoustofluidics on Slippery yet Sticky, Flexible Surfaces
por: Tao, Ran, et al.
Publicado: (2020)

Foxf2: A Novel Locus for Anterior Segment Dysgenesis Adjacent to the Foxc1 Gene
por: McKeone, Richard, et al.
Publicado: (2011)

Foxf Genes Integrate Tbx5 and Hedgehog Pathways in the Second Heart Field for Cardiac Septation
por: Hoffmann, Andrew D., et al.
Publicado: (2014)

FOXF1 mediates mesenchymal stem cell fusion-induced reprogramming of lung cancer cells
por: Wei, Hong-Jian, et al.
Publicado: (2014)

FOXF2 deficiency promotes epithelial-mesenchymal transition and metastasis of basal-like breast cancer
por: Wang, Qing-Shan, et al.
Publicado: (2015)

A 16q deletion involving FOXF1 enhancer is associated to pulmonary capillary hemangiomatosis
por: Dello Russo, Patrizia, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_mfcts46feieqea2q8s1hn0kesp