Cargando…

A Lanosteryl triterpene from Protorhus longifolia augments insulin signaling in type 1 diabetic rats

BACKGROUND: A substantial literature supports antidiabetic properties of the lanosteryl triterpene (methyl-3β-hydroxylanosta-9,24-dien-21-oate, RA-3) isolated from Protorhus longifolia stem bark. However, the molecular mechanism(s) associated with the antihyperglycemic properties of the triterpene r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ephraim, Mabhida Sihle, Rabia, Johnson, Musawenkosi, Ndlovu, Felicia, Sangweni Nonhlakanipho, Johan, Louw, Andrew, Opoku, Anthony, Mosa Rebamang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167861/ https://www.ncbi.nlm.nih.gov/pubmed/30285704 http://dx.doi.org/10.1186/s12906-018-2337-z

Ejemplares similares

Correction to: A Lanosteryl triterpene from Protorhus longifolia augments insulin signaling in type 1 diabetic rats
por: Mabhida, Sihle Ephraim, et al.
Publicado: (2018)

In Vivo Antihyperglycemic Activity of a Lanosteryl Triterpene from Protorhus longifolia
por: Mosa, Rebamang A., et al.
Publicado: (2015)

A Lanosteryl Triterpene from Protorhus longifolia Improves Glucose Tolerance and Pancreatic Beta Cell Ultrastructure in Type 2 Diabetic Rats
por: Mabhida, Sihle E., et al.
Publicado: (2017)

Molecular basis of the anti-hyperglycemic activity of RA-3 in hyperlipidemic and streptozotocin-induced type 2 diabetes in rats
por: Mabhida, Sihle Ephraim, et al.
Publicado: (2019)

In vivo anti-hyperlipidemic activity of the triterpene from the stem bark of Protorhus longifolia (Benrh) Engl
por: Machaba, Kgothatso E, et al.
Publicado: (2014)

Triterpenoids from Protorhus longifolia Exhibit Hypocholesterolemic Potential via Regulation of Cholesterol Biosynthesis and Stimulation of Low-Density Lipoprotein Uptake in HepG2 Cells
por: Ndlovu, Musawenkosi, et al.
Publicado: (2023)

A Lanosteryl Triterpene (RA-3) Exhibits Antihyperuricemic and Nephroprotective Effects in Rats
por: Hlophe, Nomadlozi Blessings, et al.
Publicado: (2020)

An In Vitro Study on the Combination Effect of Metformin and N-Acetyl Cysteine against Hyperglycaemia-Induced Cardiac Damage
por: Johnson, Rabia, et al.
Publicado: (2019)

Testicular Dysfunction Ameliorative Effect of the Methanolic Roots Extracts of Maytenus procumbens and Ozoroa paniculosa
por: Cele, Nkosinathi David, et al.
Publicado: (2017)

Evaluation of the anti-Listeria potentials of some plant-derived triterpenes
por: Penduka, Dambudzo, et al.
Publicado: (2014)

Pharmacogenomics of amlodipine and hydrochlorothiazide therapy and the quest for improved control of hypertension: a mini review
por: Johnson, Rabia, et al.
Publicado: (2019)

Phytochemical Profiling and Isolation of Bioactive Compounds from Leucosidea sericea (Rosaceae)
por: Ramabulana, Tshifhiwa, et al.
Publicado: (2022)

Identification of potential biomarkers for predicting the early onset of diabetic cardiomyopathy in a mouse model
por: Johnson, Rabia, et al.
Publicado: (2020)

Molecular insights into the pathophysiology of doxorubicin-induced cardiotoxicity: a graphical representation
por: Sangweni, Nonhlakanipho F., et al.
Publicado: (2022)

Isolation and characterization of microsatellite loci for the large-seeded tree Protorhus deflexa (Anacardiaceae)(1)
por: Sato, Hiroki, et al.
Publicado: (2013)

The Implication of Low Dose Dimethyl Sulfoxide on Mitochondrial Function and Oxidative Damage in Cultured Cardiac and Cancer Cells
por: Sangweni, Nonhlakanipho F., et al.
Publicado: (2021)

The Prophylactic Effect of Pinocembrin Against Doxorubicin-Induced Cardiotoxicity in an In Vitro H9c2 Cell Model
por: Sangweni, Nonhlakanipho F., et al.
Publicado: (2020)

Prevention of Anthracycline-Induced Cardiotoxicity: The Good and Bad of Current and Alternative Therapies
por: Sangweni, Nonhlakanipho F., et al.
Publicado: (2022)

Doxorubicin-Induced Cardiomyopathy: A Preliminary Study on the Cardioprotective Benefits of 7-Hydroxyflavanone
por: Sangweni, Nonhlakanipho F., et al.
Publicado: (2023)

In vitro and in vivo hepatotoxicity study of Afriplex™ GRT through an inflammatory response
por: Gabuza, Kwazikwakhe B., et al.
Publicado: (2022)

Prevalence of Hypertension and Its Associated Risk Factors in a Rural Black Population of Mthatha Town, South Africa
por: Sharma, Jyoti Rajan, et al.
Publicado: (2021)

Hypertension in African Populations: Review and Computational Insights
por: Mabhida, Sihle E., et al.
Publicado: (2021)

Sclerocarya birrea (Marula) Extract Inhibits Hepatic Steatosis in db/db Mice
por: Mabasa, Lawrence, et al.
Publicado: (2022)

RHEUMATOID ARTHRITIS AND ASTERCANTHA LONGIFOLIA
por: Thankamma, A.
Publicado: (1999)

Bassia longifolia (= Madhuca longifolia): Isolation of flavan-3-ols and their contribution to the antibacterial and antidiabetic activity in vitro
por: Bürkel, Peter, et al.
Publicado: (2023)

Methylenetetrahydrofolate Reductase Polymorphism (rs1801133) and the Risk of Hypertension among African Populations: A Narrative Synthesis of Literature
por: Mabhida, Sihle E., et al.
Publicado: (2022)

The association of MTHFR (rs1801133) with hypertension in an indigenous south African population
por: Mabhida, Sihle E., et al.
Publicado: (2022)

The chemistry, pharmacologic, and therapeutic applications of Polyalthia longifolia
por: Katkar, K. V., et al.
Publicado: (2010)

Bioactive Constituents from the Roots of Eurycoma longifolia
por: Ruan, Jingya, et al.
Publicado: (2019)

Effects on Photosynthetic Response and Biomass Productivity of Acacia longifolia ssp. longifolia Under Elevated CO(2) and Water-Limited Regimes
por: Javaid, Muhammad Mansoor, et al.
Publicado: (2022)

Anticancer Effects of Wild Mountain Mentha longifolia Extract in Adrenocortical Tumor Cell Models
por: Patti, Felicia, et al.
Publicado: (2020)

NF-κB Inhibitors from Eurycoma longifolia
por: Tran, Thi Van Anh, et al.
Publicado: (2014)

Investigation of some biologic activities of Swertia longifolia Boiss
por: Hajimehdipoor, H., et al.
Publicado: (2013)

Review Ergogenic Effect of Long Jack, Eurycoma Longifolia
por: Khanijo, Thasanee, et al.
Publicado: (2016)

Eurycoma longifolia—Infused Coffee—An Oral Toxicity Study
por: Ahmad, Norzahirah, et al.
Publicado: (2020)

Complete plastome sequence of Xylosma longifolia Clos. (Salicaceae)
por: Chen, Peng, et al.
Publicado: (2021)

Change in Health-Related Quality of Life among Pulmonary Tuberculosis Patients at Primary Health Care Settings in South Africa: A Prospective Cohort Study
por: Louw, Julia S., et al.
Publicado: (2016)

Triterpene einschließlich Steroide
por: Sticher, O.
Publicado: (2007)

Triterpene einschließlich Steroide
por: Sticher, Otto
Publicado: (2009)

Immunomodulatory properties of triterpenes
por: Renda, Gülin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_vtau3qk9dk3ac40310go1gr2or