Durable response to anti-PD-1 immunotherapy in epithelioid angiomyolipoma: a report on the successful treatment of a rare malignancy

BACKGROUND: Malignant angiomyolipoma is an uncommon tumor of the class of perivasciular epithelioid cell neoplasms (PEComas). These tumors are characteristically driven by deleterious mutations in the tumor suppressors TSC1 and TSC2, whose gene products typically act to inhibit mTOR. There are sever...

Descripción completa

Detalles Bibliográficos
Autores principales: Lattanzi, Michael, Deng, Fang-Ming, Chiriboga, Luis A., Femia, Alisa N., Meehan, Shane A., Iyer, Gopa, Voss, Martin H., Sundatova, Yuliya, Huang, William C., Balar, Arjun V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167873/
https://www.ncbi.nlm.nih.gov/pubmed/30285856
http://dx.doi.org/10.1186/s40425-018-0415-x

Ejemplares similares

Ejemplares similares