Complex patterns of direct and indirect association between the transcription Factor-7 like 2 gene, body mass index and type 2 diabetes diagnosis in adulthood in the Hispanic Community Health Study/Study of Latinos

BACKGROUND: Genome-wide association studies have implicated the transcription factor 7-like 2 (TCF7L2) gene in type 2 diabetes risk, and more recently, in decreased body mass index. Given the contrary direction of genetic effects on these two traits, it has been suggested that the observed associati...

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Detalles Bibliográficos
Autores principales: Fernández-Rhodes, Lindsay, Howard, Annie Green, Graff, Mariaelisa, Isasi, Carmen R., Highland, Heather M., Young, Kristin L., Parra, Esteban, Below, Jennifer E., Qi, Qibin, Kaplan, Robert C., Justice, Anne E., Papanicolaou, George, Laurie, Cathy C., Grant, Struan F. A., Haiman, Christopher, Loos, Ruth J. F., North, Kari E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167893/
https://www.ncbi.nlm.nih.gov/pubmed/30305909
http://dx.doi.org/10.1186/s40608-018-0200-x

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