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Comprehensive comparison of MetAP2 tissue and cellular expression pattern in lean and obese rodents

BACKGROUND: Methionine aminopeptidase 2 (MetAP2) cleaves the initiator methionine from nascent peptides during translation. In both preclinical and clinical studies, the pharmacological inhibition of MetAP2 in obese subjects results in the suppression of food intake and body weight loss. However, th...

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Detalles Bibliográficos
Autores principales:	Han, Jing, Tang, Yang, Lu, Mingjian, Hua, Haiqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167978/ https://www.ncbi.nlm.nih.gov/pubmed/30319281 http://dx.doi.org/10.2147/DMSO.S171109

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