The exquisitely cooperative nature of Orai1 channel activation

Yeung and Prakriya highlight new research showing that STIM1 must bind to all six Orai1 subunits to effectively activate the channel.

Detalles Bibliográficos
Autores principales: Yeung, Priscilla See-Wai, Prakriya, Murali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168242/
https://www.ncbi.nlm.nih.gov/pubmed/30217863
http://dx.doi.org/10.1085/jgp.201812172
Descripción
Sumario:Yeung and Prakriya highlight new research showing that STIM1 must bind to all six Orai1 subunits to effectively activate the channel.

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