The exquisitely cooperative nature of Orai1 channel activation

Yeung and Prakriya highlight new research showing that STIM1 must bind to all six Orai1 subunits to effectively activate the channel.

Detalles Bibliográficos
Autores principales: Yeung, Priscilla See-Wai, Prakriya, Murali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168242/
https://www.ncbi.nlm.nih.gov/pubmed/30217863
http://dx.doi.org/10.1085/jgp.201812172
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author Yeung, Priscilla See-Wai
Prakriya, Murali
author_facet Yeung, Priscilla See-Wai
Prakriya, Murali
author_sort Yeung, Priscilla See-Wai
collection PubMed
description Yeung and Prakriya highlight new research showing that STIM1 must bind to all six Orai1 subunits to effectively activate the channel.
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spelling pubmed-61682422019-04-01 The exquisitely cooperative nature of Orai1 channel activation Yeung, Priscilla See-Wai Prakriya, Murali J Gen Physiol Commentaries Yeung and Prakriya highlight new research showing that STIM1 must bind to all six Orai1 subunits to effectively activate the channel. Rockefeller University Press 2018-10-01 /pmc/articles/PMC6168242/ /pubmed/30217863 http://dx.doi.org/10.1085/jgp.201812172 Text en © 2018 Yeung and Prakriya http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentaries
Yeung, Priscilla See-Wai
Prakriya, Murali
The exquisitely cooperative nature of Orai1 channel activation
title The exquisitely cooperative nature of Orai1 channel activation
title_full The exquisitely cooperative nature of Orai1 channel activation
title_fullStr The exquisitely cooperative nature of Orai1 channel activation
title_full_unstemmed The exquisitely cooperative nature of Orai1 channel activation
title_short The exquisitely cooperative nature of Orai1 channel activation
title_sort exquisitely cooperative nature of orai1 channel activation
topic Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168242/
https://www.ncbi.nlm.nih.gov/pubmed/30217863
http://dx.doi.org/10.1085/jgp.201812172
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