Opening leads to closing: Allosteric crosstalk between the activation and inactivation gates in KcsA

Delemotte appraises new computational work revealing that the intracellular activation gate must open for C-type inactivation to occur in K(+) channels.

Detalles Bibliográficos
Autor principal: Delemotte, Lucie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168244/
https://www.ncbi.nlm.nih.gov/pubmed/30143551
http://dx.doi.org/10.1085/jgp.201812161
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author Delemotte, Lucie
author_facet Delemotte, Lucie
author_sort Delemotte, Lucie
collection PubMed
description Delemotte appraises new computational work revealing that the intracellular activation gate must open for C-type inactivation to occur in K(+) channels.
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spelling pubmed-61682442019-04-01 Opening leads to closing: Allosteric crosstalk between the activation and inactivation gates in KcsA Delemotte, Lucie J Gen Physiol Commentaries Delemotte appraises new computational work revealing that the intracellular activation gate must open for C-type inactivation to occur in K(+) channels. Rockefeller University Press 2018-10-01 /pmc/articles/PMC6168244/ /pubmed/30143551 http://dx.doi.org/10.1085/jgp.201812161 Text en © 2018 Delemotte http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentaries
Delemotte, Lucie
Opening leads to closing: Allosteric crosstalk between the activation and inactivation gates in KcsA
title Opening leads to closing: Allosteric crosstalk between the activation and inactivation gates in KcsA
title_full Opening leads to closing: Allosteric crosstalk between the activation and inactivation gates in KcsA
title_fullStr Opening leads to closing: Allosteric crosstalk between the activation and inactivation gates in KcsA
title_full_unstemmed Opening leads to closing: Allosteric crosstalk between the activation and inactivation gates in KcsA
title_short Opening leads to closing: Allosteric crosstalk between the activation and inactivation gates in KcsA
title_sort opening leads to closing: allosteric crosstalk between the activation and inactivation gates in kcsa
topic Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168244/
https://www.ncbi.nlm.nih.gov/pubmed/30143551
http://dx.doi.org/10.1085/jgp.201812161
work_keys_str_mv AT delemottelucie openingleadstoclosingallostericcrosstalkbetweentheactivationandinactivationgatesinkcsa

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