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Myoepithelial cells are a dynamic barrier to epithelial dissemination

The mammary epithelium is composed of an inner luminal and surrounding myoepithelial cell layer. The presence of cancer cells beyond the myoepithelium defines invasive breast cancer, yet the role of the myoepithelium during invasion remains unclear. We developed a 3D organotypic culture assay to mod...

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Detalles Bibliográficos
Autores principales: Sirka, Orit Katarina, Shamir, Eliah R., Ewald, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168248/
https://www.ncbi.nlm.nih.gov/pubmed/30061105
http://dx.doi.org/10.1083/jcb.201802144