Cargando…
Draxin acts as a molecular rheostat of canonical Wnt signaling to control cranial neural crest EMT
Neural crest cells undergo a spatiotemporally regulated epithelial-to-mesenchymal transition (EMT) that proceeds head to tailward to exit from the neural tube. In this study, we show that the secreted molecule Draxin is expressed in a transient rostrocaudal wave that mirrors this emigration pattern,...
Autores principales: | Hutchins, Erica J., Bronner, Marianne E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168252/ https://www.ncbi.nlm.nih.gov/pubmed/30026247 http://dx.doi.org/10.1083/jcb.201709149 |
Ejemplares similares
-
Transcriptomic Identification of Draxin-Responsive Targets During Cranial Neural Crest EMT
por: Hutchins, Erica J., et al.
Publicado: (2021) -
Sip1 mediates an E-cadherin-to-N-cadherin switch during cranial neural crest EMT
por: Rogers, Crystal D., et al.
Publicado: (2013) -
RNA-binding protein Elavl1/HuR is required for maintenance of cranial neural crest specification
por: Hutchins, Erica J, et al.
Publicado: (2022) -
A potential inhibitory function of draxin in regulating mouse trunk neural crest migration
por: Zhang, Sanbing, et al.
Publicado: (2016) -
Bimodal function of chromatin remodeler Hmga1 in neural crest induction and Wnt-dependent emigration
por: Gandhi, Shashank, et al.
Publicado: (2020)