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Transcription and mRNA export machineries SAGA and TREX-2 maintain monoubiquitinated H2B balance required for DNA repair

DNA repair is critical to maintaining genome integrity, and its dysfunction can cause accumulation of unresolved damage that leads to genomic instability. The Spt–Ada–Gcn5 acetyltransferase (SAGA) coactivator complex and the nuclear pore–associated transcription and export complex 2 (TREX-2) couple...

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Detalles Bibliográficos
Autores principales:	Evangelista, Federica M., Maglott-Roth, Anne, Stierle, Matthieu, Brino, Laurent, Soutoglou, Evi, Tora, László
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168256/ https://www.ncbi.nlm.nih.gov/pubmed/30054449 http://dx.doi.org/10.1083/jcb.201803074

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