Cargando…

KIF1Bβ mutations detected in hereditary neuropathy impair IGF1R transport and axon growth

KIF1Bβ is a kinesin-3 family anterograde motor protein essential for neuronal development, viability, and function. KIF1Bβ mutations have previously been reported in a limited number of pedigrees of Charcot-Marie-Tooth disease type 2A (CMT2A) neuropathy. However, the gene responsible for CMT2A is st...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Fang, Takahashi, Hironori, Tanaka, Yosuke, Ichinose, Sotaro, Niwa, Shinsuke, Wicklund, Matthew P., Hirokawa, Nobutaka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168269/ https://www.ncbi.nlm.nih.gov/pubmed/30126838 http://dx.doi.org/10.1083/jcb.201801085

Ejemplares similares

Intracellular transport, molecular motors, KIFs and related diseases
por: Hirokawa, Nobutaka
Publicado: (2014)

An activity-dependent local transport regulation via degradation and synthesis of KIF17 underlying cognitive flexibility
por: Iwata, Suguru, et al.
Publicado: (2020)

Mutation in KIF5A c.610C>T Causing Hereditary Spastic Paraplegia with Axonal Sensorimotor Neuropathy
por: Cuchanski, Mathieu, et al.
Publicado: (2018)

Left-Right Asymmetry and Kinesin Superfamily Protein KIF3A: New Insights in Determination of Laterality and Mesoderm Induction by kif3A(−) (/−) Mice Analysis
por: Takeda, Sen, et al.
Publicado: (1999)

De novo mutations in KIF1A-associated neuronal disorder (KAND) dominant-negatively inhibit motor activity and axonal transport of synaptic vesicle precursors
por: Anazawa, Yuzu, et al.
Publicado: (2022)

Defect in Synaptic Vesicle Precursor Transport and Neuronal Cell Death in KIF1A Motor Protein–deficient Mice
por: Yonekawa, Yoshiaki, et al.
Publicado: (1998)

KIF13B enhances the endocytosis of LRP1 by recruiting LRP1 to caveolae
por: Kanai, Yoshimitsu, et al.
Publicado: (2014)

Preferential binding of a kinesin-1 motor to GTP-tubulin–rich microtubules underlies polarized vesicle transport
por: Nakata, Takao, et al.
Publicado: (2011)

KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway
por: Wan, Yuansong, et al.
Publicado: (2022)

Defects in Axonal Elongation and Neuronal Migration in Mice with Disrupted tau and map1b Genes
por: Takei, Yosuke, et al.
Publicado: (2000)

Microtubules provide directional cues for polarized axonal transport through interaction with kinesin motor head
por: Nakata, Takao, et al.
Publicado: (2003)

Kinesin Superfamily Protein 3 (Kif3) Motor Transports Fodrin-Associating Vesicles Important for Neurite Building
por: Takeda, Sen, et al.
Publicado: (2000)

Axonal transport deficit in a KIF5A(–/–) mouse model
por: Karle, Kathrin N., et al.
Publicado: (2012)

A de novo dominant mutation in KIF1A associated with axonal neuropathy, spasticity and autism spectrum disorder
por: Tomaselli, Pedro J., et al.
Publicado: (2017)

Propagation and Selectivity of Axonal Loss in Leber Hereditary Optic Neuropathy
por: Coussa, Razek Georges, et al.
Publicado: (2019)

Motor domain-mediated autoinhibition dictates axonal transport by the kinesin UNC-104/KIF1A
por: Cong, Dezi, et al.
Publicado: (2021)

Defects in Axonal Transport in Inherited Neuropathies
por: Beijer, Danique, et al.
Publicado: (2019)

KIF1A mediates axonal transport of BACE1 and identification of independently moving cargoes in living SCG neurons
por: Hung, Christy O. Y., et al.
Publicado: (2016)

FIGNL1 associates with KIF1Bβ and BICD1 to restrict dynein transport velocity during axon navigation
por: Atkins, Melody, et al.
Publicado: (2019)

A hereditary spastic paraplegia mutation in kinesin-1A/KIF5A disrupts neurofilament transport
por: Wang, Lina, et al.
Publicado: (2010)

Structural basis for CRMP2-induced axonal microtubule formation
por: Niwa, Shinsuke, et al.
Publicado: (2017)

Binding and transport of SFPQ-RNA granules by KIF5A/KLC1 motors promotes axon survival
por: Fukuda, Yusuke, et al.
Publicado: (2020)

Axonal Transport as an In Vivo Biomarker for Retinal Neuropathy
por: Le Roux, Lucia G., et al.
Publicado: (2020)

IGF1R regulates retrograde axonal transport of signalling endosomes in motor neurons
por: Fellows, Alexander D, et al.
Publicado: (2020)

Author Correction: Propagation and Selectivity of Axonal Loss in Leber Hereditary Optic Neuropathy
por: Coussa, Razek Georges, et al.
Publicado: (2020)

IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling
por: Yoneyama, Yosuke, et al.
Publicado: (2018)

Axonal Transport Impairment in Chemotherapy-Induced Peripheral Neuropathy
por: Nicolini, Gabriella, et al.
Publicado: (2015)

Axonal transport deficits in the pathogenesis of diabetic peripheral neuropathy
por: Yang, Cunqing, et al.
Publicado: (2023)

Selective axonal transport through branch junctions is directed by growth cone signaling and mediated by KIF1/kinesin-3 motors
por: Tymanskyj, Stephen R., et al.
Publicado: (2022)

An ALS‐associated KIF5A mutant forms oligomers and aggregates and induces neuronal toxicity
por: Nakano, Juri, et al.
Publicado: (2022)

Modeling Reactive Oxygen Species-Induced Axonal Loss in Leber Hereditary Optic Neuropathy
por: Lambiri, Darius W., et al.
Publicado: (2022)

Motility and microtubule depolymerization mechanisms of the Kinesin-8 motor, KIF19A
por: Wang, Doudou, et al.
Publicado: (2016)

Kif1b is essential for mRNA localization in oligodendrocytes and development of myelinated axons
por: Lyons, David A., et al.
Publicado: (2009)

KIF2A regulates the development of dentate granule cells and postnatal hippocampal wiring
por: Homma, Noriko, et al.
Publicado: (2018)

Visualization of the Dynamics of Synaptic Vesicle and Plasma Membrane Proteins in Living Axons
por: Nakata, Takao, et al.
Publicado: (1998)

KIF1A variants are a frequent cause of autosomal dominant hereditary spastic paraplegia
por: Pennings, Maartje, et al.
Publicado: (2019)

Disruption of Axonal Transport in Motor Neuron Diseases
por: Ikenaka, Kensuke, et al.
Publicado: (2012)

Huntingtin recruits KIF1A to transport synaptic vesicle precursors along the mouse axon to support synaptic transmission and motor skill learning
por: Vitet, Hélène, et al.
Publicado: (2023)

Ankle Fracture in Hereditary Sensory Neuropathy Type 1
por: Loh, Jeremy, et al.
Publicado: (2021)

Demyelination in hereditary sensory neuropathy type‐1C
por: Saba, Sadaf, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_bkdfnpjkn35avahsc0obvtilqk