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KIF1Bβ mutations detected in hereditary neuropathy impair IGF1R transport and axon growth

KIF1Bβ is a kinesin-3 family anterograde motor protein essential for neuronal development, viability, and function. KIF1Bβ mutations have previously been reported in a limited number of pedigrees of Charcot-Marie-Tooth disease type 2A (CMT2A) neuropathy. However, the gene responsible for CMT2A is st...

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Detalles Bibliográficos
Autores principales:	Xu, Fang, Takahashi, Hironori, Tanaka, Yosuke, Ichinose, Sotaro, Niwa, Shinsuke, Wicklund, Matthew P., Hirokawa, Nobutaka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168269/ https://www.ncbi.nlm.nih.gov/pubmed/30126838 http://dx.doi.org/10.1083/jcb.201801085

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