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Starvation induces rapid degradation of selective autophagy receptors by endosomal microautophagy
It is not clear to what extent starvation-induced autophagy affects the proteome on a global scale and whether it is selective. In this study, we report based on quantitative proteomics that cells during the first 4 h of acute starvation elicit lysosomal degradation of up to 2–3% of the proteome. Th...
Autores principales: | Mejlvang, Jakob, Olsvik, Hallvard, Svenning, Steingrim, Bruun, Jack-Ansgar, Abudu, Yakubu Princely, Larsen, Kenneth Bowitz, Brech, Andreas, Hansen, Tom E., Brenne, Hanne, Hansen, Terkel, Stenmark, Harald, Johansen, Terje |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168274/ https://www.ncbi.nlm.nih.gov/pubmed/30018090 http://dx.doi.org/10.1083/jcb.201711002 |
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