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VPS13: A lipid transfer protein making contacts at multiple cellular locations
The evolutionarily conserved VPS13 proteins localize to multiple membrane contact sites though their function and regulation has been elusive. Bean et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201804111) found that competitive adaptors control the different localizations of yeast Vps13p,...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Rockefeller University Press
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168276/ https://www.ncbi.nlm.nih.gov/pubmed/30181317 http://dx.doi.org/10.1083/jcb.201808151 |
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author | Gao, Mingming Yang, Hongyuan |
author_facet | Gao, Mingming Yang, Hongyuan |
author_sort | Gao, Mingming |
collection | PubMed |
description | The evolutionarily conserved VPS13 proteins localize to multiple membrane contact sites though their function and regulation has been elusive. Bean et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201804111) found that competitive adaptors control the different localizations of yeast Vps13p, while Kumar et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201807019) provide biochemical and structural evidence for VPS13 proteins in the nonvesicular transport of phospholipids. |
format | Online Article Text |
id | pubmed-6168276 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-61682762019-04-01 VPS13: A lipid transfer protein making contacts at multiple cellular locations Gao, Mingming Yang, Hongyuan J Cell Biol Commentaries The evolutionarily conserved VPS13 proteins localize to multiple membrane contact sites though their function and regulation has been elusive. Bean et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201804111) found that competitive adaptors control the different localizations of yeast Vps13p, while Kumar et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201807019) provide biochemical and structural evidence for VPS13 proteins in the nonvesicular transport of phospholipids. Rockefeller University Press 2018-10-01 /pmc/articles/PMC6168276/ /pubmed/30181317 http://dx.doi.org/10.1083/jcb.201808151 Text en © 2018 Gao and Yang http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Commentaries Gao, Mingming Yang, Hongyuan VPS13: A lipid transfer protein making contacts at multiple cellular locations |
title | VPS13: A lipid transfer protein making contacts at multiple cellular locations |
title_full | VPS13: A lipid transfer protein making contacts at multiple cellular locations |
title_fullStr | VPS13: A lipid transfer protein making contacts at multiple cellular locations |
title_full_unstemmed | VPS13: A lipid transfer protein making contacts at multiple cellular locations |
title_short | VPS13: A lipid transfer protein making contacts at multiple cellular locations |
title_sort | vps13: a lipid transfer protein making contacts at multiple cellular locations |
topic | Commentaries |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168276/ https://www.ncbi.nlm.nih.gov/pubmed/30181317 http://dx.doi.org/10.1083/jcb.201808151 |
work_keys_str_mv | AT gaomingming vps13alipidtransferproteinmakingcontactsatmultiplecellularlocations AT yanghongyuan vps13alipidtransferproteinmakingcontactsatmultiplecellularlocations |