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COMRADES determines in vivo RNA structures and interactions

RNA structural flexibility underlies fundamental biological processes, but there are no methods to explore the multiple conformations adopted by RNAs in vivo. We developed Crosslinking Of Matched RNAs And Deep Sequencing (COMRADES) for in-depth RNA conformation capture, and a pipeline for retrieval...

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Detalles Bibliográficos
Autores principales:	Ziv, Omer, Gabryelska, Marta M., Lun, Aaron T.L., Gebert, Luca F.R., Sheu-Gruttadauria, Jessica, Meredith, Luke W., Liu, Zhong-Yu, Kwok, Chun Kit, Qin, Cheng-Feng, Macrae, Ian J., Goodfellow, Ian, Marioni, John C., Kudla, Grzegorz, Miska, Eric A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168409/ https://www.ncbi.nlm.nih.gov/pubmed/30202058 http://dx.doi.org/10.1038/s41592-018-0121-0

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