GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers

Treatment failure in solid tumors occurs due to the survival of specific subpopulations of cells that possess tumor-initiating (TIC) phenotypes. Studies have implicated G protein-coupled-receptors (GPCRs) in cancer progression and the acquisition of TIC phenotypes. Many of the implicated GPCRs signa...

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Detalles Bibliográficos
Autores principales: Rasheed, Suhail Ahmed Kabeer, Leong, Hui Sun, Lakshmanan, Manikandan, Raju, Anandhkumar, Dadlani, Dhivya, Chong, Fui-Teen, Shannon, Nicholas B, Rajarethinam, Ravisankar, Skanthakumar, Thakshayeni, Tan, Ern Yu, Hwang, Jacqueline Siok Gek, Lim, Kok Hing, Tan, Daniel Shao-Weng, Ceppi, Paolo, Wang, Mei, Tergaonkar, Vinay, Casey, Patrick J., Iyer, N. Gopalakrishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168473/
https://www.ncbi.nlm.nih.gov/pubmed/29255247
http://dx.doi.org/10.1038/s41388-017-0038-6

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