Human and mouse albumin bind their respective neonatal Fc receptors differently

Albumin has a serum half-life of three weeks in humans and is utilized to extend the serum persistence of drugs that are genetically fused or conjugated directly to albumin or albumin-binding molecules. Responsible for the long half-life is FcRn that protects albumin from intracellular degradation....

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Detalles Bibliográficos
Autores principales: Nilsen, Jeannette, Bern, Malin, Sand, Kine Marita Knudsen, Grevys, Algirdas, Dalhus, Bjørn, Sandlie, Inger, Andersen, Jan Terje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168492/
https://www.ncbi.nlm.nih.gov/pubmed/30279529
http://dx.doi.org/10.1038/s41598-018-32817-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168492/
https://www.ncbi.nlm.nih.gov/pubmed/30279529
http://dx.doi.org/10.1038/s41598-018-32817-0

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