Computational design of chemogenetic and optogenetic split proteins

Controlling protein activity with chemogenetics and optogenetics has proven to be powerful for testing hypotheses regarding protein function in rapid biological processes. Controlling proteins by splitting them and then rescuing their activity through inducible reassembly offers great potential to c...

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Detalles Bibliográficos
Autores principales: Dagliyan, Onur, Krokhotin, Andrey, Ozkan-Dagliyan, Irem, Deiters, Alexander, Der, Channing J., Hahn, Klaus M., Dokholyan, Nikolay V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168510/
https://www.ncbi.nlm.nih.gov/pubmed/30279442
http://dx.doi.org/10.1038/s41467-018-06531-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168510/
https://www.ncbi.nlm.nih.gov/pubmed/30279442
http://dx.doi.org/10.1038/s41467-018-06531-4

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