Chemogenetic generation of hydrogen peroxide in the heart induces severe cardiac dysfunction

Oxidative stress plays an important role in the pathogenesis of many disease states. In the heart, reactive oxygen species are linked with cardiac ischemia/reperfusion injury, hypertrophy, and heart failure. While this correlation between ROS and cardiac pathology has been observed in multiple model...

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Detalles Bibliográficos
Autores principales: Steinhorn, Benjamin, Sorrentino, Andrea, Badole, Sachin, Bogdanova, Yulia, Belousov, Vsevolod, Michel, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168530/
https://www.ncbi.nlm.nih.gov/pubmed/30279532
http://dx.doi.org/10.1038/s41467-018-06533-2

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