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Urinary Exosomal and cell-free DNA Detects Somatic Mutation and Copy Number Alteration in Urothelial Carcinoma of Bladder

Urothelial bladder carcinoma (UBC) is characterized by a large number of genetic alterations. DNA from urine is a promising source for liquid biopsy in urological malignancies. We aimed to assess the availability of cell-free DNA (cfDNA) and exosomal DNA (exoDNA) in urine as a source for liquid biop...

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Detalles Bibliográficos
Autores principales:	Lee, Dong Hyeon, Yoon, Hana, Park, Sanghui, Kim, Jeong Seon, Ahn, Young-Ho, Kwon, Kihwan, Lee, Donghwan, Kim, Kwang Hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168539/ https://www.ncbi.nlm.nih.gov/pubmed/30279572 http://dx.doi.org/10.1038/s41598-018-32900-6

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