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2D polarization imaging as a low-cost fluorescence method to detect α-synuclein aggregation ex vivo in models of Parkinson’s disease

A hallmark of Parkinson’s disease is the formation of large protein-rich aggregates in neurons, where α-synuclein is the most abundant protein. A standard approach to visualize aggregation is to fluorescently label the proteins of interest. Then, highly fluorescent regions are assumed to contain agg...

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Detalles Bibliográficos
Autores principales:	Camacho, Rafael, Täuber, Daniela, Hansen, Christian, Shi, Juanzi, Bousset, Luc, Melki, Ronald, Li, Jia-Yi, Scheblykin, Ivan G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168587/ https://www.ncbi.nlm.nih.gov/pubmed/30302401 http://dx.doi.org/10.1038/s42003-018-0156-x

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