Cargando…

A New Approach for Loading Anticancer Drugs Into Mesenchymal Stem Cell-Derived Exosome Mimetics for Cancer Therapy

Exosomes derived from mesenchymal stem cells (MSCs) have been evaluated for their potential to be used as drug delivery vehicles. Synthetically personalized exosome mimetics (EMs) could be the alternative vesicles for drug delivery. In this study, we aimed to isolate EMs from human MSCs. Cells were...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kalimuthu, Senthilkumar, Gangadaran, Prakash, Rajendran, Ramya Lakshmi, Zhu, Liya, Oh, Ji Min, Lee, Ho Won, Gopal, Arunnehru, Baek, Se Hwan, Jeong, Shin Young, Lee, Sang-Woo, Lee, Jaetae, Ahn, Byeong-Cheol
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168623/ https://www.ncbi.nlm.nih.gov/pubmed/30319428 http://dx.doi.org/10.3389/fphar.2018.01116

Ejemplares similares

In vivo Non-invasive Imaging of Radio-Labeled Exosome-Mimetics Derived From Red Blood Cells in Mice
por: Gangadaran, Prakash, et al.
Publicado: (2018)

Migration of mesenchymal stem cells to tumor xenograft models and in vitro drug delivery by doxorubicin
por: Kalimuthu, Senthilkumar, et al.
Publicado: (2018)

Targeting and Therapy of Glioblastoma in a Mouse Model Using Exosomes Derived From Natural Killer Cells
por: Zhu, Liya, et al.
Publicado: (2018)

Exosomes Derived From Natural Killer Cells Exert Therapeutic Effect in Melanoma
por: Zhu, Liya, et al.
Publicado: (2017)

Reverting iodine avidity of radioactive-iodine refractory thyroid cancer with a new tyrosine kinase inhibitor (K905-0266) excavated by high-throughput NIS (sodium iodide symporter) enhancer screening platform using dual reporter gene system
por: Oh, Ji Min, et al.
Publicado: (2018)

Regulated Mesenchymal Stem Cells Mediated Colon Cancer Therapy Assessed by Reporter Gene Based Optical Imaging
por: Kalimuthu, Senthilkumar, et al.
Publicado: (2018)

In Vivo Tracking of Chemokine Receptor CXCR4-Engineered Mesenchymal Stem Cell Migration by Optical Molecular Imaging
por: Kalimuthu, Senthilkumar, et al.
Publicado: (2017)

Corrigendum to “In Vivo Tracking of Chemokine Receptor CXCR4-Engineered Mesenchymal Stem Cell Migration by Optical Molecular Imaging”
por: Kalimuthu, Senthilkumar, et al.
Publicado: (2020)

Radioiodine labeling and in vivo trafficking of extracellular vesicles
por: Hong, Chae Moon, et al.
Publicado: (2021)

Extracellular vesicles derived from MSCs activates dermal papilla cell in vitro and promotes hair follicle conversion from telogen to anagen in mice
por: Rajendran, Ramya Lakshmi, et al.
Publicado: (2017)

A new bioluminescent reporter system to study the biodistribution of systematically injected tumor-derived bioluminescent extracellular vesicles in mice
por: Gangadaran, Prakash, et al.
Publicado: (2017)

Correction: A new bioluminescent reporter system to study the biodistribution of systematically injected tumor-derived bioluminescent extracellular vesicles in mice
por: Gangadaran, Prakash, et al.
Publicado: (2020)

New Optical Imaging Reporter-labeled Anaplastic Thyroid Cancer-Derived Extracellular Vesicles as a Platform for In Vivo Tumor Targeting in a Mouse Model
por: Gangadaran, Prakash, et al.
Publicado: (2018)

Natural Killer Cell (NK-92MI)-Based Therapy for Pulmonary Metastasis of Anaplastic Thyroid Cancer in a Nude Mouse Model
por: Zhu, Liya, et al.
Publicado: (2017)

Different Expression of Thyroid-Specific Proteins in Thyroid Cancer Cells between 2-Dimensional (2D) and 3-Dimensional (3D) Culture Environment
por: Oh, Ji Min, et al.
Publicado: (2022)

Macrophage-Derived Extracellular Vesicle Promotes Hair Growth
por: Rajendran, Ramya Lakshmi, et al.
Publicado: (2020)

Advances in Molecular Imaging Strategies for In Vivo Tracking of Immune Cells
por: Lee, Ho Won, et al.
Publicado: (2016)

Targeting GLI1 Transcription Factor for Restoring Iodine Avidity with Redifferentiation in Radioactive-Iodine Refractory Thyroid Cancers
por: Oh, Ji Min, et al.
Publicado: (2022)

Application of In Vivo Imaging Techniques for Monitoring Natural Killer Cell Migration and Tumor Infiltration
por: Gangadaran, Prakash, et al.
Publicado: (2020)

Genetically engineered suicide gene in mesenchymal stem cells using a Tet-On system for anaplastic thyroid cancer
por: Kalimuthu, Senthilkumar, et al.
Publicado: (2017)

Development of an athyroid mouse model using (131)I ablation after preparation with a low-iodine diet
por: Oh, Ji Min, et al.
Publicado: (2017)

Identification of Angiogenic Cargo in Extracellular Vesicles Secreted from Human Adipose Tissue-Derived Stem Cells and Induction of Angiogenesis In Vitro and In Vivo
por: Gangadaran, Prakash, et al.
Publicado: (2021)

Application of extracellular vesicles from mesenchymal stem cells promotes hair growth by regulating human dermal cells and follicles
por: Rajendran, Ramya Lakshmi, et al.
Publicado: (2022)

In Vivo therapeutic potential of mesenchymal stem cell-derived extracellular vesicles with optical imaging reporter in tumor mice model
por: Kalimuthu, Senthilkumar, et al.
Publicado: (2016)

Noninvasive in vivo cell tracking using molecular imaging: A useful tool for developing mesenchymal stem cell-based cancer treatment
por: Rajendran, Ramya Lakshmi, et al.
Publicado: (2020)

Extracellular Vesicle- and Extracellular Vesicle Mimetics-Based Drug Delivery Systems: New Perspectives, Challenges, and Clinical Developments
por: Gangadaran, Prakash, et al.
Publicado: (2020)

Engineered Nanovesicles from Fibroblasts Modulate Dermal Papillae Cells In Vitro and Promote Human Hair Follicle Growth Ex Vivo
por: Rajendran, Ramya Lakshmi, et al.
Publicado: (2022)

Extracellular Vesicles Act as Nano-Transporters of Tyrosine Kinase Inhibitors to Revert Iodine Avidity in Thyroid Cancer
por: Rajendran, Ramya Lakshmi, et al.
Publicado: (2021)

Interleukin-4 Receptor Targeting Peptide Decorated Extracellular Vesicles as a Platform for In Vivo Drug Delivery to Thyroid Cancer
por: Gangadaran, Prakash, et al.
Publicado: (2022)

CAR T-Cell-Based gene therapy for cancers: new perspectives, challenges, and clinical developments
por: Jogalekar, Manasi P., et al.
Publicado: (2022)

The emerging role of exosomes in innate immunity, diagnosis and therapy
por: Gangadaran, Prakash, et al.
Publicado: (2023)

Application of Cell-Derived Extracellular Vesicles and Engineered Nanovesicles for Hair Growth: From Mechanisms to Therapeutics
por: Gangadaran, Prakash, et al.
Publicado: (2022)

Biological Production of an Integrin αvβ3 Targeting Imaging Probe and Functional Verification
por: Hwang, Mi-Hye, et al.
Publicado: (2015)

An Update on the Effectiveness of Probiotics in the Prevention and Treatment of Cancer
por: Sankarapandian, Vidya, et al.
Publicado: (2022)

Evolution and Clinical Advances of Platelet-Rich Fibrin in Musculoskeletal Regeneration
por: Narayanaswamy, Ragunanthan, et al.
Publicado: (2023)

Osteogenic and Chondrogenic Potential of Periosteum-Derived Mesenchymal Stromal Cells: Do They Hold the Key to the Future?
por: Jeyaraman, Madhan, et al.
Publicado: (2021)

Is Culture Expansion Necessary in Autologous Mesenchymal Stromal Cell Therapy to Obtain Superior Results in the Management of Knee Osteoarthritis?—Meta-Analysis of Randomized Controlled Trials
por: Muthu, Sathish, et al.
Publicado: (2021)

Advancing Regenerative Cellular Therapies in Non-Scarring Alopecia
por: Anudeep, Talagavadi Channaiah, et al.
Publicado: (2022)

Current Role of Intra-Articular Injections of Platelet-Rich Plasma in Adhesive Capsulitis of Shoulder: A Systematic Review
por: Harna, Bushu, et al.
Publicado: (2022)

Molecular Imaging: A Useful Tool for the Development of Natural Killer Cell-Based Immunotherapies
por: Gangadaran, Prakash, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ho2fgmtsc1dr9mtkb44up1u1t2