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Cationic Amphipathic Antimicrobial Peptides Perturb the Inner Membrane of Germinated Spores Thus Inhibiting Their Outgrowth

The mode of action of four cationic amphipathic antimicrobial peptides (AMPs) was evaluated against the non-pathogenic, Gram-positive, spore-forming bacterium, Bacillus subtilis. The AMPs were TC19, TC84, BP2, and the lantibiotic Nisin A. TC19 and TC84 were derived from the human thrombocidin-1. Bac...

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Detalles Bibliográficos
Autores principales: Omardien, Soraya, Drijfhout, Jan Wouter, Zaat, Sebastian A., Brul, Stanley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168669/
https://www.ncbi.nlm.nih.gov/pubmed/30319583
http://dx.doi.org/10.3389/fmicb.2018.02277

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