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Acute Myeloid Leukemia Cells Express ICOS Ligand to Promote the Expansion of Regulatory T Cells

CD4(+)CD25(+)Foxp3(+) regulatory T cells (Tregs) accumulate in bone marrow microenvironment in acute myeloid leukemia (AML). However, little is known about how the tumor environment including tumor cells themselves affects this process. Here we demonstrated that AML cells expressed inducible T-cell...

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Detalles Bibliográficos
Autores principales:	Han, Yixiang, Dong, Yuqing, Yang, Qianqian, Xu, Wanling, Jiang, Songfu, Yu, Zhijie, Yu, Kang, Zhang, Shenghui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168677/ https://www.ncbi.nlm.nih.gov/pubmed/30319662 http://dx.doi.org/10.3389/fimmu.2018.02227

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