Cost Implications of Reactive Versus Prospective Testing for Dihydropyrimidine Dehydrogenase Deficiency in Patients With Colorectal Cancer: A Single-Institution Experience

BACKGROUND: Severe toxicity is experienced by a substantial minority of patients receiving fluoropyrimidine-based chemotherapy, with approximately 20% of these severe toxicities attributable to polymorphisms in the DPYD gene. The DPYD codes for the enzyme dihydropyrimidine dehydrogenase (DPD) import...

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Detalles Bibliográficos
Autores principales: Murphy, Con, Byrne, Stephen, Ahmed, Gul, Kenny, Andrew, Gallagher, James, Harvey, Harry, O’Farrell, Eoin, Bird, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168732/
https://www.ncbi.nlm.nih.gov/pubmed/30288154
http://dx.doi.org/10.1177/1559325818803042

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