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Vascular toxicities with VEGF inhibitor therapies–focus on hypertension and arterial thrombotic events

The vascular endothelial growth factor (VEGF) signaling pathway (VSP) fulfills a cardinal role in endothelial cells and its inhibition has profound cardiovascular impact. This is true not only for the normal vasculature but also for the tumor vasculature when VSP inhibitors are used as anti-angiogen...

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Detalles Bibliográficos
Autores principales: Touyz, Rhian M., Herrmann, Sandra M.S., Herrmann, Joerg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168784/
https://www.ncbi.nlm.nih.gov/pubmed/29703600
http://dx.doi.org/10.1016/j.jash.2018.03.008