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Vascular toxicities with VEGF inhibitor therapies–focus on hypertension and arterial thrombotic events
The vascular endothelial growth factor (VEGF) signaling pathway (VSP) fulfills a cardinal role in endothelial cells and its inhibition has profound cardiovascular impact. This is true not only for the normal vasculature but also for the tumor vasculature when VSP inhibitors are used as anti-angiogen...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168784/ https://www.ncbi.nlm.nih.gov/pubmed/29703600 http://dx.doi.org/10.1016/j.jash.2018.03.008 |