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Data on COA-Cl administration to the APP/PS2 double-transgenic mouse model of Alzheimer׳s disease: Improved hippocampus-dependent learning and unchanged spontaneous physical activity
We herein present behavioral data regarding whether COA-Cl, a novel adenosine-like nucleic acid analog that promotes angiogenesis and features neuroprotective roles, improves cognitive and behavioral deficits in a murine model for Alzheimer׳s disease (AD). COA-Cl induced significant spatial memory i...
Autores principales: | Kishimoto, Yasushi, Tsukamoto, Ikuko, Nishigawa, Atsuko, Nishimoto, Akiko, Kirino, Yutaka, Kato, Yoshihisa, Konishi, Ryoji, Maruyama, Tokumi, Sakakibara, Norikazu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168792/ https://www.ncbi.nlm.nih.gov/pubmed/30294639 http://dx.doi.org/10.1016/j.dib.2018.09.044 |
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