Melanoma cell-secreted exosomal miR-155-5p induce proangiogenic switch of cancer-associated fibroblasts via SOCS1/JAK2/STAT3 signaling pathway

BACKGROUND: Cancer-associated fibroblasts (CAFs) have been widely reported to promote tumor angiogenesis. However, the underlying mechanisms of the proangiogenic switch of CAFs remain poorly understood. This study aims to clarify the mechanisms underlying the proangiogenic switch of CAFs. METHODS: N...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaocheng, Yan, Tinglin, Huang, Chunming, Xu, Zhi, Wang, Lin, Jiang, Erhui, Wang, Hui, Chen, Yang, Liu, Ke, Shao, Zhe, Shang, Zhengjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169013/
https://www.ncbi.nlm.nih.gov/pubmed/30285793
http://dx.doi.org/10.1186/s13046-018-0911-3

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