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Molecular characterization of three novel perforins in common carp (Cyprinus carpio L.) and their expression patterns during larvae ontogeny and in response to immune challenges

BACKGROUND: In the host immune system, perforin is a cytotoxic effector molecule that eliminate virus-infected and malignant cells. Moreover, some recent studies also imply the involvement of perforin in antibacterial immunity. Common carp (Cyprinus carpio L.), one of the most economically important...

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Detalles Bibliográficos
Autores principales: Li, Ting, Wang, Lei, Zhang, Yonghuan, Guo, Xinyi, Chen, Xinze, Zhang, Fumiao, Yang, Guiwen, Wen, Wujun, Li, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169072/
https://www.ncbi.nlm.nih.gov/pubmed/30285759
http://dx.doi.org/10.1186/s12917-018-1613-y