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Molecular characterization of three novel perforins in common carp (Cyprinus carpio L.) and their expression patterns during larvae ontogeny and in response to immune challenges
BACKGROUND: In the host immune system, perforin is a cytotoxic effector molecule that eliminate virus-infected and malignant cells. Moreover, some recent studies also imply the involvement of perforin in antibacterial immunity. Common carp (Cyprinus carpio L.), one of the most economically important...
Autores principales: | Li, Ting, Wang, Lei, Zhang, Yonghuan, Guo, Xinyi, Chen, Xinze, Zhang, Fumiao, Yang, Guiwen, Wen, Wujun, Li, Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169072/ https://www.ncbi.nlm.nih.gov/pubmed/30285759 http://dx.doi.org/10.1186/s12917-018-1613-y |
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