An ABCG2 non-substrate anticancer agent FL118 targets drug-resistant cancer stem-like cells and overcomes treatment resistance of human pancreatic cancer

BACKGROUND: Pancreatic cancer is a deadly disease with a very low 5-year patient survival rate of 6–8%. The major challenges of eliminating pancreatic cancer are treatment resistance and stromal barriers to optimal drug access within the tumor. Therefore, effective molecular targeting drugs with hig...

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Detalles Bibliográficos
Autores principales: Ling, Xiang, Wu, Wenjie, Fan, Chuandong, Xu, Chao, Liao, Jianqun, Rich, Laurie J., Huang, Ruea-Yea, Repasky, Elizabeth A., Wang, Xinjiang, Li, Fengzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169080/
https://www.ncbi.nlm.nih.gov/pubmed/30285798
http://dx.doi.org/10.1186/s13046-018-0899-8

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