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Investigation of PP2A and Its Endogenous Inhibitors in Neuroblastoma Cell Survival and Tumor Growth

High-risk neuroblastoma continues to carry a poor prognosis. Nearly 50% of these tumors relapse following extensive treatment regimens. Protein phosphatase 2A (PP2A), a tumor suppressor, has been shown to be downregulated in many human cancers via multiple mechanisms including upregulation of its en...

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Detalles Bibliográficos
Autores principales: Williams, Adele P., Garner, Evan F., Waters, Alicia M., Stafman, Laura L., Aye, Jamie M., Markert, Hooper, Stewart, Jerry E., Beierle, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169101/
https://www.ncbi.nlm.nih.gov/pubmed/30286326
http://dx.doi.org/10.1016/j.tranon.2018.09.011