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Stevioside Prevents Wear Particle-Induced Osteolysis by Inhibiting Osteoclastogenesis and Inflammatory Response via the Suppression of TAK1 Activation

Aseptic loosening and periprosthetic osteolysis are the leading causes of total joint arthroplasty failure, which occurs as a result of chronic inflammatory response and enhanced osteoclast activity. Here we showed that stevioside, a natural compound isolated from Stevia rebaudiana, exhibited preven...

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Detalles Bibliográficos
Autores principales:	Meng, Jiahong, Zhou, Chenhe, Hu, Bin, Luo, Mengmeng, Yang, Yute, Wang, Yangxin, Wang, Wei, Jiang, Guangyao, Hong, Jianqiao, Li, Sihao, Wu, Haobo, Yan, Shigui, Yan, Weiqi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169369/ https://www.ncbi.nlm.nih.gov/pubmed/30319406 http://dx.doi.org/10.3389/fphar.2018.01053

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