A Novel Mutation in Brain Tumor Causes Both Neural Over-Proliferation and Neurodegeneration in Adult Drosophila

A screen for neuroprotective genes in Drosophila melanogaster led to the identification of a mutation that causes extreme, progressive loss of adult brain neuropil in conjunction with massive brain overgrowth. We mapped the mutation to the brain tumor (brat) locus, which encodes a tripartite motif-N...

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Detalles Bibliográficos
Autores principales: Loewen, Carin, Boekhoff-Falk, Grace, Ganetzky, Barry, Chtarbanova, Stanislava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2018
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169379/
https://www.ncbi.nlm.nih.gov/pubmed/30126833
http://dx.doi.org/10.1534/g3.118.200627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169379/
https://www.ncbi.nlm.nih.gov/pubmed/30126833
http://dx.doi.org/10.1534/g3.118.200627

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