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Accounting for Programmed Ribosomal Frameshifting in the Computation of Codon Usage Bias Indices
Experimental evidence shows that synonymous mutations can have important consequences on genetic fitness. Many organisms display codon usage bias (CUB), where synonymous codons that are translated into the same amino acid appear with distinct frequency. Within genomes, CUB is thought to arise from s...
Autores principales: | Garcia, Victor, Zoller, Stefan, Anisimova, Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169388/ https://www.ncbi.nlm.nih.gov/pubmed/30111621 http://dx.doi.org/10.1534/g3.118.200185 |
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