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Double Selection Enhances the Efficiency of Target-AID and Cas9-Based Genome Editing in Yeast
CRISPR-Cas9 loss of function (LOF) and base editing screens are powerful tools in genetics and genomics. Yeast is one of the main models in these fields, but has only recently started to adopt this new toolkit for high throughput experiments. We developed a double selection strategy based on co-sele...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Genetics Society of America
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169390/ https://www.ncbi.nlm.nih.gov/pubmed/30097473 http://dx.doi.org/10.1534/g3.118.200461 |