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Potent therapeutic efficacy of an alphavirus replicon DNA vaccine expressing human papilloma virus E6 and E7 antigens

Cervical cancer develops as a result of infection with high-risk human papillomavirus (HPV) through persistent expression of early proteins E6 and E7. Our group pioneered a recombinant viral vector system based on Semliki Forest virus (SFV) for vaccination against cervical cancer. The most striking...

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Detalles Bibliográficos
Autores principales: van de Wall, Stephanie, Ljungberg, Karl, Ip, Peng Peng, Boerma, Annemarie, Knudsen, Maria L., Nijman, Hans W., Liljeström, Peter, Daemen, Toos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169581/
https://www.ncbi.nlm.nih.gov/pubmed/30288352
http://dx.doi.org/10.1080/2162402X.2018.1487913

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