Macrophages in radiation injury: a new therapeutic target

Radiotherapy can induce toxicity in healthy tissues such as radiation-induced fibrosis (RIF), and macrophages are proposed as new profibrogenic cells. In this Point-of-View, we summarize the role of the immune response in ionizing radiation injury, and we focus on macrophages as a new therapeutic ta...

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Detalles Bibliográficos
Autores principales: Meziani, Lydia, Deutsch, Eric, Mondini, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Point-of-View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169587/
https://www.ncbi.nlm.nih.gov/pubmed/30288363
http://dx.doi.org/10.1080/2162402X.2018.1494488
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author Meziani, Lydia
Deutsch, Eric
Mondini, Michele
author_facet Meziani, Lydia
Deutsch, Eric
Mondini, Michele
author_sort Meziani, Lydia
collection PubMed
description Radiotherapy can induce toxicity in healthy tissues such as radiation-induced fibrosis (RIF), and macrophages are proposed as new profibrogenic cells. In this Point-of-View, we summarize the role of the immune response in ionizing radiation injury, and we focus on macrophages as a new therapeutic target in RIF.
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spelling pubmed-61695872018-10-04 Macrophages in radiation injury: a new therapeutic target Meziani, Lydia Deutsch, Eric Mondini, Michele Oncoimmunology Point-of-View Radiotherapy can induce toxicity in healthy tissues such as radiation-induced fibrosis (RIF), and macrophages are proposed as new profibrogenic cells. In this Point-of-View, we summarize the role of the immune response in ionizing radiation injury, and we focus on macrophages as a new therapeutic target in RIF. Taylor & Francis 2018-07-23 /pmc/articles/PMC6169587/ /pubmed/30288363 http://dx.doi.org/10.1080/2162402X.2018.1494488 Text en © 2018 Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
spellingShingle Point-of-View
Meziani, Lydia
Deutsch, Eric
Mondini, Michele
Macrophages in radiation injury: a new therapeutic target
title Macrophages in radiation injury: a new therapeutic target
title_full Macrophages in radiation injury: a new therapeutic target
title_fullStr Macrophages in radiation injury: a new therapeutic target
title_full_unstemmed Macrophages in radiation injury: a new therapeutic target
title_short Macrophages in radiation injury: a new therapeutic target
title_sort macrophages in radiation injury: a new therapeutic target
topic Point-of-View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169587/
https://www.ncbi.nlm.nih.gov/pubmed/30288363
http://dx.doi.org/10.1080/2162402X.2018.1494488
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