The aryl hydrocarbon receptor regulates nucleolar activity and protein synthesis in MYC-expressing cells

MYC enhances protein synthesis by regulating genes involved in ribosome biogenesis and protein translation. Here, we show that MYC-induced protein translation is mediated by the transcription factor aryl hydrocarbon receptor (AHR), which is induced by MYC in colonic cells. AHR promotes protein synth...

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Detalles Bibliográficos
Autores principales: Lafita-Navarro, M. Carmen, Kim, Min, Borenstein-Auerbach, Nofit, Venkateswaran, Niranjan, Hao, Yi-Heng, Ray, Roshni, Brabletz, Thomas, Scaglioni, Pier Paolo, Shay, Jerry W., Conacci-Sorrell, Maralice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169836/
https://www.ncbi.nlm.nih.gov/pubmed/30254109
http://dx.doi.org/10.1101/gad.313007.118

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