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Chronic oral application of a periodontal pathogen results in brain inflammation, neurodegeneration and amyloid beta production in wild type mice

BACKGROUND: The results from cross sectional and longitudinal studies show that periodontitis is closely associated with cognitive impairment (CI) and Alzhemer’s Disease (AD). Further, studies using animal model of periodontitis and human post-mortem brain tissues from subjects with AD strongly sugg...

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Detalles Bibliográficos
Autores principales:	Ilievski, Vladimir, Zuchowska, Paulina K., Green, Stefan J., Toth, Peter T., Ragozzino, Michael E., Le, Khuong, Aljewari, Haider W., O’Brien-Simpson, Neil M., Reynolds, Eric C., Watanabe, Keiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169940/ https://www.ncbi.nlm.nih.gov/pubmed/30281647 http://dx.doi.org/10.1371/journal.pone.0204941

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