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Long-term results of posterior cruciate ligament tear with or without reconstruction: A nationwide, population-based cohort study

BACKGROUND: There is increasing interest in the long-term outcomes of patients with posterior cruciate ligament (PCL) tears following conservative treatment or reconstruction. However, limited information is available regarding these results because of the relative rarity of cases and lack of long-t...

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Autores principales: Wang, Sheng-Hao, Chien, Wu-Chien, Chung, Chi-Hsiang, Wang, Yung-Chih, Lin, Leou-Chyr, Pan, Ru-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169976/
https://www.ncbi.nlm.nih.gov/pubmed/30281658
http://dx.doi.org/10.1371/journal.pone.0205118
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author Wang, Sheng-Hao
Chien, Wu-Chien
Chung, Chi-Hsiang
Wang, Yung-Chih
Lin, Leou-Chyr
Pan, Ru-Yu
author_facet Wang, Sheng-Hao
Chien, Wu-Chien
Chung, Chi-Hsiang
Wang, Yung-Chih
Lin, Leou-Chyr
Pan, Ru-Yu
author_sort Wang, Sheng-Hao
collection PubMed
description BACKGROUND: There is increasing interest in the long-term outcomes of patients with posterior cruciate ligament (PCL) tears following conservative treatment or reconstruction. However, limited information is available regarding these results because of the relative rarity of cases and lack of long-term follow-up. PURPOSE: The goals of this study are to (1) compare the occurrence of secondary meniscal tears, osteoarthritis (OA) or subsequent total knee replacement (TKR) in patients with or without PCL injury, and (2) evaluate the potential protective effect of PCL reconstruction against long-term sequela in patients with PCL deficiency. STUDY DESIGN: Cohort study; Level of evidence, 3 METHODS: This retrospective cohort study evaluated the long-term results of PCL deficiency with or without reconstruction in Taiwan based on data from the National Health Insurance Research Database (NHIRD) from 2000 to 2015. The cumulative incidence rates of meniscus tear, OA and TKR were analyzed using the Kaplan-Meier estimator. Cox proportional hazards models were applied to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). RESULTS: A total of 4,169 patients diagnosed with PCL tear from 2000 to 2015 in Taiwan were included in the study. There was a higher cumulative incidence of meniscus tear (1.13%), OA (2.71%) and subsequent TKR (0.91%) among patients with a PCL tear than among patients without one (0.22%, 1.90%, 0.62%; all p < 0.05). PCL reconstruction patients had a decreased cumulative incidence of meniscus tear (0.41%), OA (2.30%) and subsequent TKR (0.48%) compared with non-reconstructed patients (2.44%, 3.46%, 1.69%; all p < 0.05). After adjusting for covariates, PCL-injured patients who underwent reconstruction within one year after PCL injury showed a significantly lower risk of subsequent sequelae than those who never underwent reconstruction (within 1 month: adjusted HR = 0.390, 95% CI = 0.284–0.535; 1 month to 1 year: adjusted HR = 0.546, 95% CI = 0.398–0.748). CONCLUSIONS: Patients with PCL tears have a significantly higher risk of meniscus tear, OA and subsequent TKR than patients without PCL tears. PCL reconstruction could decrease the cumulative incidence of these outcomes. The results suggest that PCL-injured patients should undergo reconstruction as early as possible (within one year) to reduce the risk of further degeneration.
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spelling pubmed-61699762018-10-19 Long-term results of posterior cruciate ligament tear with or without reconstruction: A nationwide, population-based cohort study Wang, Sheng-Hao Chien, Wu-Chien Chung, Chi-Hsiang Wang, Yung-Chih Lin, Leou-Chyr Pan, Ru-Yu PLoS One Research Article BACKGROUND: There is increasing interest in the long-term outcomes of patients with posterior cruciate ligament (PCL) tears following conservative treatment or reconstruction. However, limited information is available regarding these results because of the relative rarity of cases and lack of long-term follow-up. PURPOSE: The goals of this study are to (1) compare the occurrence of secondary meniscal tears, osteoarthritis (OA) or subsequent total knee replacement (TKR) in patients with or without PCL injury, and (2) evaluate the potential protective effect of PCL reconstruction against long-term sequela in patients with PCL deficiency. STUDY DESIGN: Cohort study; Level of evidence, 3 METHODS: This retrospective cohort study evaluated the long-term results of PCL deficiency with or without reconstruction in Taiwan based on data from the National Health Insurance Research Database (NHIRD) from 2000 to 2015. The cumulative incidence rates of meniscus tear, OA and TKR were analyzed using the Kaplan-Meier estimator. Cox proportional hazards models were applied to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). RESULTS: A total of 4,169 patients diagnosed with PCL tear from 2000 to 2015 in Taiwan were included in the study. There was a higher cumulative incidence of meniscus tear (1.13%), OA (2.71%) and subsequent TKR (0.91%) among patients with a PCL tear than among patients without one (0.22%, 1.90%, 0.62%; all p < 0.05). PCL reconstruction patients had a decreased cumulative incidence of meniscus tear (0.41%), OA (2.30%) and subsequent TKR (0.48%) compared with non-reconstructed patients (2.44%, 3.46%, 1.69%; all p < 0.05). After adjusting for covariates, PCL-injured patients who underwent reconstruction within one year after PCL injury showed a significantly lower risk of subsequent sequelae than those who never underwent reconstruction (within 1 month: adjusted HR = 0.390, 95% CI = 0.284–0.535; 1 month to 1 year: adjusted HR = 0.546, 95% CI = 0.398–0.748). CONCLUSIONS: Patients with PCL tears have a significantly higher risk of meniscus tear, OA and subsequent TKR than patients without PCL tears. PCL reconstruction could decrease the cumulative incidence of these outcomes. The results suggest that PCL-injured patients should undergo reconstruction as early as possible (within one year) to reduce the risk of further degeneration. Public Library of Science 2018-10-03 /pmc/articles/PMC6169976/ /pubmed/30281658 http://dx.doi.org/10.1371/journal.pone.0205118 Text en © 2018 Wang et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Wang, Sheng-Hao
Chien, Wu-Chien
Chung, Chi-Hsiang
Wang, Yung-Chih
Lin, Leou-Chyr
Pan, Ru-Yu
Long-term results of posterior cruciate ligament tear with or without reconstruction: A nationwide, population-based cohort study
title Long-term results of posterior cruciate ligament tear with or without reconstruction: A nationwide, population-based cohort study
title_full Long-term results of posterior cruciate ligament tear with or without reconstruction: A nationwide, population-based cohort study
title_fullStr Long-term results of posterior cruciate ligament tear with or without reconstruction: A nationwide, population-based cohort study
title_full_unstemmed Long-term results of posterior cruciate ligament tear with or without reconstruction: A nationwide, population-based cohort study
title_short Long-term results of posterior cruciate ligament tear with or without reconstruction: A nationwide, population-based cohort study
title_sort long-term results of posterior cruciate ligament tear with or without reconstruction: a nationwide, population-based cohort study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169976/
https://www.ncbi.nlm.nih.gov/pubmed/30281658
http://dx.doi.org/10.1371/journal.pone.0205118
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