Cross-talk among writers, readers, and erasers of m(6)A regulates cancer growth and progression

The importance of RNA methylation in biological processes is an emerging focus of investigation. We report that altering m(6)A levels by silencing either N(6)-adenosine methyltransferase METTL14 (methyltransferase-like 14) or demethylase ALKBH5 (ALKB homolog 5) inhibits cancer growth and invasion. M...

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Detalles Bibliográficos
Autores principales: Panneerdoss, Subbarayalu, Eedunuri, Vijay K., Yadav, Pooja, Timilsina, Santosh, Rajamanickam, Subapriya, Viswanadhapalli, Suryavathi, Abdelfattah, Nourhan, Onyeagucha, Benjamin C., Cui, Xiadong, Lai, Zhao, Mohammad, Tabrez A., Gupta, Yogesh K., Huang, Tim Hui-Ming, Huang, Yufei, Chen, Yidong, Rao, Manjeet K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170038/
https://www.ncbi.nlm.nih.gov/pubmed/30306128
http://dx.doi.org/10.1126/sciadv.aar8263

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