Cargando…
A Batf3/Nlrp3/IL-18 Axis Promotes Natural Killer Cell IL-10 Production during Listeria monocytogenes Infection
The bacterial pathogen Listeria monocytogenes (Lm) capitalizes on natural killer (NK) cell production of regulatory interleukin (IL)-10 to establish severe systemic infections. Here, we identify regulators of this IL-10 secretion. We show that IL-18 signals to NK cells license their ability to produ...
Autores principales: | Clark, Sarah E., Schmidt, Rebecca L., McDermott, Daniel S., Lenz, Laurel L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170157/ https://www.ncbi.nlm.nih.gov/pubmed/29847790 http://dx.doi.org/10.1016/j.celrep.2018.04.106 |
Ejemplares similares
-
Distinct Licensing of IL-18 and IL-1β Secretion in Response to NLRP3 Inflammasome Activation
por: Schmidt, Rebecca L., et al.
Publicado: (2012) -
Pulmonary insults exacerbate susceptibility to oral Listeria monocytogenes infection through the production of IL-10 by NK cells
por: Bortell, Nikki, et al.
Publicado: (2021) -
Myeloid cell responsiveness to interferon-gamma is sufficient for initial resistance to Listeria monocytogenes
por: Eshleman, Emily M., et al.
Publicado: (2020) -
Mucosal CD8 T Cell Responses Are Shaped by Batf3-DC After Foodborne Listeria monocytogenes Infection
por: Imperato, Jessica Nancy, et al.
Publicado: (2020) -
BATF3 is sufficient for the induction of Il9 expression and can compensate for BATF during Th9 cell differentiation
por: Lee, Woo Ho, et al.
Publicado: (2019)