Zebrafish blastomere screen identifies retinoic acid suppression of MYB in adenoid cystic carcinoma

Pluripotent cells have been used to probe developmental pathways that are involved in genetic diseases and oncogenic events. To find new therapies that would target MYB-driven tumors, we developed a pluripotent zebrafish blastomere culture system. We performed a chemical genetic screen and identifie...

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Detalles Bibliográficos
Autores principales: Mandelbaum, Joseph, Shestopalov, Ilya A., Henderson, Rachel E., Chau, Nicole G., Knoechel, Birgit, Wick, Michael J., Zon, Leonard I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170170/
https://www.ncbi.nlm.nih.gov/pubmed/30209067
http://dx.doi.org/10.1084/jem.20180939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170170/
https://www.ncbi.nlm.nih.gov/pubmed/30209067
http://dx.doi.org/10.1084/jem.20180939

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